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These differences in clinical features suggest a different pathogenesis of parkinsonism in these 2 patient groups. The strong evidence of cerebrovascular disease in the VP group and the differences in clinical features support the concept of VP as a distinct clinical entity. We conclude that compared to PD, patients with parkinsonism associated with vascular disease are more likely to present with gait difficulty and postural instability rather than tremor, have a history of stroke and risk factors for stroke and fail to respond to levodopa therapy. |
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basal ganglia,infarction CAT scan CAT scan,abnormal cerebrovascular accident cerebrovascular disease falling gait disorder hypertension MRI MRI,abnormal neurologic signs Parkinson disease Parkinson disease,arteriosclerotic Parkinson disease,asymmetric onset Parkinson disease,L-dopa nonresponsive Parkinson disease,tremor,absence of Parkinsonism syndrome postural abnormality pyramidal tract dysfunction review article risk factors urinary incontinence
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