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Eighty-two percent of the patients with sarcoidosis with neurologic symptoms referable to the CNS had findings revealed by MR imaging. However, eight (40%) of 20 cranial nerve deficits seen at clinical examination of 13 patients were not se en at contrast-enhanced MR imaging, and 50% of the patients with symptoms referable to the pituitary axis had no abnormal findings on routine contrast-enhanced MR images. In contradistinction, 44% of 18 cranial nerves in nine patients with MR evidence of involvement had no symptoms referable to the involved cranial nerve. Clinical and radiologic deterioration occurred more commonly with leptomeningeal and enhancing brain parenchymal lesions. MR imaging can be used to confirm clinical suspicion and to s how subclinical disease and the response of pathologic lesions to treatment. |
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cranial nerve enhancement cranial nerve palsies cranial neuropathy cranial neuropathy,multiple facial nerve palsy MRI MRI,abnormal MRI,contrast enhanced MRI,false negative MRI,serial MRI,spinal cord pituitary pituitary,dysfunction pituitary,lesion of prognosis review article sarcoidosis sarcoidosis,CNS treatment of neurologic disorder
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