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The most common imaging finding in NBS patients who had neural parenchymal involvement was a mesodiencephalic junction lesion with edema extending along certain long tracts in the brain stem and diencephalon in 46% of the patients. The ne xt most common location of involvement was the pontobulbar region, seen in 40% of the cases. Three primary cervical spinal cord lesions and one case of isolated optic nerve involvement were observed. The parenchymal distribution of lesions in NBS appear s to support the hypothesis of small-vessel vasculitis; mainly, venular involvement. The anatomic distribution of intraaxial veins of the CNS explains the predominant involvement of the brain stem structures observed in our patients. This pattern of les ion distribution might help to differentiate NBS from other vasculitides as well as from the inflammatory-demyelinating diseases of the CNS, such as multiple sclerosis. |
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basal ganglia,lesion of
Behcet's syndrome
brainstem,lesion of
cervical spine
hypothalamus
MRI
MRI,abnormal
MRI,contrast enhanced
MRI,serial
MRI,spinal cord
optic nerve,lesion of
review article
small vessel disease
small vessel vasculitis
spinal cord,cervical
spinal cord,lesion of
thalamus,lesion of
vasculitides
white matter disease
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