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The North American Symptomatic Carotid Endarterectomy Trial, Surgical Results in 1415 Patients
Stroke 30:1751-1758,1745, Ferguson,G.G.,et al, 1999
See this aricle in Pubmed

Article Abstract
In 1415 patients there were 92 perioperative outcome events, for an overall rate of 6.5%. At 30 days the results were as follows: death, 1.1%; disabling stroke, 1.8%; and nondisabling stroke, 3.7%. At 90 days, because of improvement in the neurological status of patients judged to have been disabled at 30 days, the results were as follows: death, 1.1%, disabling stroke, 0.9%; and nondisabling stroke, 4.5%. Thirty events occurred intraoperatively; 62 were delayed. Most strokes resulte d from thromboembolism. Five baseline variables were predictive of increased surgical risk: hemispheric versus retinal transient ischemic attack as the qualifying event, left-sided procedure, contralateral carotid occlusion, ipsilateral ischemic lesion o n CT scan, and irregular or ulcerated ipsilateral plaque. History of coronary artery disease with prior cardiac procedure was associated with reduced risk. The risk of perioperative wound complications was 9.3%, and that of cranial nerve injuries was 8. 6%; most were of mild severity. At 8 years, the risk of disabling ipsilateral stroke was 5.7%, and that of any ipsilateral stroke was 17.1%. The overall rate of perioperative stroke and death was 6.5%, but the rate of permanently disabling stroke and de ath was only 2.0%. Other surgical complications were rarely clinically important. Carotid endarterectomy is a durable procedure.
 
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cerebrovascular accident
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