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Treatment of Posterior Circulation Ischemia with Extracranial Percutaneous Balloon Angioplasty and Stent Placement
Stroke 30:2073-2085, Malek,A.M.,et al, 1999
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Article Abstract
Balloon angioplasty with intravascular stent placement was performed in 13 vertebral artery lesions (10 at the origin, 3 in the cervical segment) and in 8 subclavian lesions. The presenting stenosis was 75% (50% to 100%) and was reduced to 4.5% (0% to 20%) after stenting. Six of the patients with proximal subclavian stenosis demonstrated angiographic evidence of subclavian steal, which resolved in all cases after treatment. All patients showed improvement in symptoms after the procedur e except for 1 who developed a hemispheric stroke after thrombotic occlusion of an untreated cavernous carotid artery stenosis (rate of major stroke and mortality=4.8%). One patient (4.8%) had a periprocedural transient ischemic attack (TIA), and none ha d minor stroke. At long-term follow-up (mean=20.7 +/= 3.6 months) of the surviving 20 patients, 12 (57.1%) remained symptom free, 4 (19%) had at most 1 TIA over a 3-month period, 2 (9.5%) had at most 1 TIA per month, and 2 (9.5%) had persistent symptoms. There were no clinically evident infarcts during the follow-up period. Endovascular treatment using balloon angioplasty with intravascular stent placement for symptomatic stenotic lesions resulting in VBI that is unresponsive to medical therapy appears to be of benefit in this high-risk subset of patients with poor collateral flow.
 
Related Tags
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arterial dissection
arterial dissection,vertebral
endovascular therapy
neuroradiology,interventional
subclavian steal syndrome
transluminal angioplasty,vertebral artery
treatment of neurologic disorder
vertebral artery stenosis
vertebral-basilar insufficiency

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