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Unilateral thalamic DBS was associated with significant improvements in tremor and dominant-hand fine visuomotor coordination. Statistically significant but clinically modest gains were observed on tasks of visuoperceptual and constructio nal ability, visual attention, delayed word list recognition, and prose recall. Only lexical verbal fluency declined significantly after surgery. Patients rated themselves as less anxious after surgery, and they perceived their quality of life as impro ved significantly. In particular, patients reported improved quality of life with respect to activities of daily living, stigma, motional well-being, and communication. Unilateral thalamic DBS for ET is cognitively safe and associated with improvements in anxiety and quality of life in the near term and in the absence of operative complications. Patients were better able to carry out activities of daily living after surgery, and they reported improvement in several psychosocial domains of quality of li fe. |
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benign essential tremor
psychosocial aspects
quality of life
stimulation,deep brain
treatment of neurologic disorder
tremor
tremor,surgical treatment of
tremor,thalamic stimulation for suppression of
tremor,treatment of
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