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MR findings were abnormal in 18 of the 21 patients. The most common features was spinal cord atrophy (n = 15), typically involving the thoracic cord with or without cervical cord involvement, followed by intrinsic cord signal abnormality ( n = 6), and normal-appearing cord (n= 3). Three patients had both cord atrophy and intrinsic cord signal abnormality. The cord signal abnormality was diffuse, without predilection for any specific distribution pattern. Enhancement was not seen in any o f the 10 patients who received intravenous contrast material. Only one of 16 patients with moderate to severe myelopathy had normal MR findings, as compared with two of five patients with mild myelopathy. MR findings in the spinal cord are abnormal in t he majority of patients with AIDS-associated myelopathy, typically showing spinal cord atrophy, with or without intrinsic cord signal abnormality. Patients with moderate to severe myelopathy have an increased frequency of spinal cord abnormalities, but a definite correlation between clinical severity of myelopathy and extent of MR abnormalities remains to be established. |
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acquired immunodeficiency syndrome
acquired immunodeficiency syndrome myelopathy
human immunodeficiency virus type 1
MRI
MRI,abnormal
MRI,false negative
MRI,spinal cord
MRI,spinal cord,increased intramedullary cord signal
MRI,spine
myelomalacia
myelopathy
myelopathy,vacuolar
spinal cord,lesion of
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