|
|
|
|
|
Click Here to return To Results
|
|
|
|
Thirty-three aneurysms were found in 25 (4%; 95% confidence interval [CI], 3=6%) of 626 relatives. Thirteen (8%) of 169 relatives who refused screening had MR-related reasons; an additional six persons could not be screened because of con traindications for MR imaging (pregnancy, n = 1; claustrophobia, n=5). The positive predictive value of MR angiography was 100% (95% CI, 79-100%) for "definite" aneurysms and 58% (95% CI, 28-85%) for "possible" aneurysms. Sensitivity of MR angiography w as estimated at 83% (95% CI, 65-94%) and specificity at 97% (95% CI, 94-98%). Interobserver agreement in the evaluation of MR angiograms was poor (kappa < .30), probably because different diagnostic strategies used by individual observers resulted in diff erent use of the assessment category "possible aneurysm." MR angiography is a feasible screening tool for detection of intracranial aneurysms. Positive predictive value, sensitivity, and specificity are acceptable when at least two neuroradiologists ind ependently assess MR angiograms. |
|
(click to filter results - removes previous filter)
aneurysm
aneurysm,intracranial
aneurysm,intracranial,familial
aneurysm,intracranial,screening for
aneurysm,unruptured
familial
interobserver agreement
MRI,angiography
review article
subarachnoid hemorrhage
|
Click Here to return To Results
|
|