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Twenty patients were identified. Nine had hematologic malignancies (HMs) and 11 had solid tumors (STs). The median interval from cancer diagnosis to presentation was 4 months for HMs and 20 months for STs. The most common symptom was heada che. MRI and MRV correlated in all but three patients, and MRV was more sensitive in four patients. The most frequently involved cerebral Sinus was the superior sagittal sinus. Multiple sinuses were affected in 8 of 19 patients. Five patients Had a cerebral or subarachnoid hemorrhage and three had infarction. Disorders of coagulation were the most frequent etiology in patients with HM; compression or invasion of the cerebral sinus from dural/calvarial metastasis was the main cause in those with ST. Treatment was directed at the underlying cause. Ten of 20 patients improved clinically and 3 of 6 patients improved radiologically. MRI and MRV can diagnose CST accurately in cancer patients. Causes of CST depen d on cancer type, and treatment varies with etiology. Most patients have a good outcome. |
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