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Highly Active Antiretroviral Therapy for Patients with AIDS Dementia Complex: Effect on MR Imaging Findings and Clinical Course AJNR 21:670-678, Thurnher,M.M.,et al, 2000 See this aricle in Pubmed Article Abstract Initial MR imaging revealed white matter signal abnormalities on lon-TR images without mass effect and without enhancement on postcontrast images, consistent with HIV encephalopathy. Lesions were located in the basal ganglia and posterior fossa in two patients. All four patients showed progression of white matter disease on the first follow-up MR scan (mean, 6 months). On subsequent scans, regression was seen in three patients and stabilization of white matter disease was observed in one patient. Increases in CD4+ count and decreases in viral load below the limit of quantification were present in all patients. Although our patient population was small, the results suggest that disease regression in patients with AIDS dementia complex after treatment with highly active antiretroviral therapy can be characterized and monitored by MR imaging.

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(click to filter results - removes previous filter) acquired immunodeficiency syndrome acquired immunodeficiency syndrome dementia complex antiviral agents dementia dementia,treatment of encephalitis,human immunodeficiency virus type 1 highly active antiretroviral therapy MRI MRI,abnormal MRI,disappearing lesion on treatment of neurologic disorder

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