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Intravenous Valproate is Well Tolerated in Unstable Patients with Status Epilepticus Neurol 55:722-724, Sinha,S. & Naritoku,D.K., 2000 See this aricle in Pubmed Article Abstract The authors reviewed hospital records of 13 patients with status epilepticus and hypotension who received IV valproate therapy. Most patients were elderly (74.4 +/= 12.5 [SD] years) and received a loading dose of valproate of 25.1 +/= 5.0 mg/kg (range 14.7 to 32.7), at a rate of 36.6 +/= 25.1 mg/min (range 6.3 to 100). There were no significant changes in blood pressure, pulse, or use of vasopressors. The data suggest that valproate loading is well tolerated, even in patients with cardiovascular instability.

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(click to filter results - removes previous filter) hypotension,systemic old age,neurology of seizure seizure,elderly seizure,treatment of sodium valproate sodium valproate,intravenous status epilepticus treatment of neurologic disorder

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