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Diffusion-weighted MR Imaging in a Case of Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Strokelike Episodes
AJNR 22:269-272, Yonemura,K.,et al, 2001
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Article Abstract
In a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS), both T2- and diffusion-weighted MR imaging revealed lesions as hyperintense areas in the occipital lobes early after strokelike episo des. In these lesions, no significant reduction in apparent diffusion coefficient was noted. Apparent diffusion coefficient mapping may help to differentiate strokelike episodes in MELAS from acute ischemic stroke. The strokelike episodes may be relate d to vasogenic edema and hyperperfusion, which were suggested by our single-photon emission CT and MR imaging studies.
 
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MELAS syndrome
MRI
MRI,ADC maps
MRI,diffusion weighted
single photon emission computed tomography

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