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Safety and Efficacy of Pallidal or Subthalamic Nucleus Stimulation in Advanced PD
Neurol 56:548-551, Volkmann,J.,et al, 2001
See this aricle in Pubmed
Article Abstract
The authors retrospectively compared 1-year results of bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN; n = 16) and internal pallidum (GPi) (n = 11) in advanced PD and found about equal improvement in "off" period moto r symptoms, dyskinesias, and fluctuations. STN stimulation reduced medication requirements by 65% and required significantly less electrical power. These advantages contrasted with need for more intensive postoperative monitoring and a higher incidence of adverse events related to levodopa withdrawal.
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drug withdrawal
globus pallidus,stimulation
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Parkinson disease
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stimulation,deep brain
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