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A Clinical Trial of Estrogen-Replacement Therapy After Ischemic Stroke NEJM 345:1243-1249, Viscoli,C.M.,et al, 2001 See this aricle in Pubmed Article Abstract Estradiol does not reduce mortality or the recurrence of stroke in postmenopausal women with cerebrovascular disease. This therapy should not be prescribed for the secondary prevention of cerebrovascular disease.

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