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What is the risk of thrombolysis in patients with acute stroke who might recover without treatment? In the National Institute of Neurological Disorders and Stroke rt-PA for Acute Stroke Trial, 2.6% of patients taking placebo showed spontane ous 24-hour recovery, compared to 11.5% of recombinant tissue-type plasminogen activator (rt-PA)-treated patients (p < 0.001). There were no symptomatic ICH in the patients taking placebo; one hypertensive, rt-PA-treated patient hemorrhaged. Assuming th e National Institute of Neurological Disorders and Stroke protocol is followed rigorously, patients with acute stroke rarely recover spontaneously and the thrombolytic risk is low. |
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cerebrovascular accident
cerebrovascular accident,acute management of
cerebrovascular accident,nontreatment of
cerebrovascular accident,prognosis in
cerebrovascular accident,spontaneous improvement after
cerebrovascular accident,thrombolytic agents in treatment
fibrinolytic agents
fibrinolytic agents,complications
prognosis
tissue plasminogen activator,intravenous
transient ischemic attack
treatment of neurologic disorder
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