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Dopamine Transporter Brain Imaging to Assess the Effects of Pramipexole vs Levodopa on Parkinson Disease Progression
JAMA 287:1653-1661, Parkinson Study Group, 2002
See this aricle in Pubmed

Article Abstract
Patients initially treated with pramipexole demonstrated a reduction in loss of striatal [123I]B-CIT uptake, a marker of dopamine neuron degeneration, compared with those initially treated with levodopa, during a 46-month period. These imag ing data highlight the need to further compare imaging and clinical end points of PD progression in long-term studies.
 
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adverse drug reaction
controversies in neurology
dopamine agonist
L-dopa
L-dopa,drug interactions with and side effects of
neuronal degeneration
Parkinson disease
Parkinson disease,treatment of
pramipexole
single photon emission computed tomography

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