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Early treatment with interferon beta-1a is effective in reducing conversion to clinically definite multiple sclerosis and in slowing progressive loss of brain tissue in patients with clinically isolated syndromes. The modest correlation between new lesion formation and brain volume decrease suggests that inflammatory and neurodegenerative processes are, at least party, dissociated from the earliest clinical stage of multiple sclerosis onwards. |
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axonal degeneration brain atrophy brain volume hydrocephalus,exvacuo interferon interferon beta 1-a MRI MRI,abnormal MRI,volumetry multiple sclerosis multiple sclerosis,conversion to clinically definite multiple sclerosis,monosymptomatic multiple sclerosis,treatment of multiple sclerosis,treatment of,first attack treatment of neurologic disorder ventricular enlargement
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