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Acute Methotrexate Neurotoxicity: Findings on Diffusion-Weighted Imaging and Correlation with Clinical Outcome AJNR 25:1688-1695, Rollins,N.,et al, 2004 See this aricle in Pubmed Article Abstract Diffusion abnormalities in acute MTX neurotoxicity indicated cerebral dysfunction but not necessarily overt structural injury to the cerebrum. Subsequent demyelination or gliosis could not be predicted on the basis of diffusion abnormalities. A single strokelike episode with diffusion abnormalities should not necessarily prompt modification of potentially curative chemotherapeutic regimens.

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(click to filter results - removes previous filter) cerebral edema cerebral edema,cytotoxic chemotherapy,CNS treatment and complications with intrathecal chemotherapy methotrexate MRI MRI,abnormal MRI,diffusion weighted neurotoxic prognosis

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