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Progressive Multifocal Leukoencephalopathy After Natalizumab Therapy for Crohns Disease
NEJM 353:362-368, Van Assche,G.,et al, 2005
See this aricle in Pubmed
Article Abstract
The prior diagnosis of fatal astrocytoma in a 60-year-old man with Crohns disease treated with natalizumab, a monoclonal antibody against ?4 integrins, was reclassified as JC virus-related progressive multiocal leukoencephalopathy (PML).
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JC virus
MRI
MRI,abnormal
natalizumab
progressive multifocal leucoencephalopathy
regional enteritis
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