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Primary CNS Lymphoma Complicating Treatment of Myasthenia Gravis with Mycophenolate Mofetil
Neurol 65:639-641, Vernino,S.,et al, 2005
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Article Abstract
Mycophenolate mofetil (MM), an immunosuppressant used after organ transplantation, is also used from treatment of autoimmune myasthenia gravis (MG). A patients with generalized MG was effectively managed with MM but developed CNS lymphoma after 3 years of treatment. Primary CNS lymphoma regressed on withdrawal of MM. Despite minimal short-term side effects and apparent efficacy, chronic treatment of MG with MM mayb e associated with increased risk of lymphoproliferative disorders.
 
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adverse drug reaction
Epstein-Barr virus
iatrogenic neurologic disorders
immunosuppression
immunosuppressive agents
lymphoma
lymphoma,primary of CNS
myasthenia gravis
mycophenolate

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