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Intrathecal Baclofen Withdrawal Mimicking Sepsis
J Emerg Med 24:423-427, Kao,L.W.,e tal, 2003
See this aricle in Pubmed

Article Abstract
Emergency physicians will likely treat patients with baclofen withdrawal or overdose as this treatment becomes more widespread. The syndrome of baclofen withdrawal presents with altered mental status, fever, tachycardia, hypertension or hypotension, seizures, and rebound spasticity, and may be fatal if not treated appropriately. Baclofen withdrawal may mimic other disease including sepsis, meningitis, autonomic dysreflexia, malignant hyperthermia, or neuroleptic malignant syndrome. Treatment consists of supportive care, reinstitution of baclofen, benzodiazepines, and diagnosis and eventual repair of intrathecal pump and catheter malfunction.
 
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adverse drug reaction
antispasticity drugs
autonomic dysfunction
baclofen
baclofen withdrawal
coma
drug withdrawal
fever
hypertension
hypotension,systemic
intrathecal antispasticity drugs
intrathecal pump
mental status,abnormal
misdiagnosis
mortality
seizure
spasticity
treatment of neurologic disorder

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