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Cortical Laminar Necrosis Related to Prolonged Focal Status Epilepticus
JNNP 77:104-106, Donaire,A.,et al, 2006
See this aricle in Pubmed

Article Abstract
Cortical laminar necrosis (CLN) is radiologically defined as high intensity cortical lesions on TI weighted MRI images following a gyral distribution. Histopathologically, CLN is characterised by pannecrosis of the cortex involving neurones, glial cells, and blood vessels. It has been reported to be associated with hypoxia, metabolic disturbances, drugs, and infections. We present two patients who developed CLN and permanent neurological deficits after prolonged and repeated focal status epilepticus. The possible mechanisms leading to CLN in these patients are discussed, together with the implications of prompt and aggressive treatment in similar cases.
 
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epilepsia partialis continua
laminar necrosis,cortical
seizure,complications following
status epilepticus

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