Neurology Specific Literature Search   
 
[home][thesaurus]
    
Click Here to return To Results

 

Thromboembolic Adverse Events After Use of Recombinant Human Coagulation Factor VIIa
JAMA 295:293-298, OConnell,K.A.,et al, 2006
See this aricle in Pubmed

Article Abstract
Most reported thromboembolic AEs followed the use of rFVIIa for unlabeled indications and occurred in arterial and venous systems, often resulting in serious morbidity and mortality. Analysis of the relationship between AEs and rFVIIa is hindered by concomitant medications, preexisting medical conditions, confounding by indication, and inherent limitations of passive surveillance. Randomized controlled trials are needed to establish the safety and efficacy of rFVIIa in patients without hemophilia.
 
Related Tags
(click to filter results - removes previous filter)

adverse drug reaction
cerebrovascular accident
mortality
myocardial infarction
myocardial injury
pulmonary embolism
recombinant activated factor VII
thrombophlebitis

Click Here to return To Results