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CT and MR Imaging of Neuroaxonal Leukodystrophy Presenting as Early-Onset Frontal Dementia
AJNR 27:1037-1039, Mascalchi,M.,et al, 2006
See this aricle in Pubmed
Article Abstract
CT and MR imaging showed diffuse changes of the frontal white matter and genu of the corpus callosum with minimal atrophy and not contrast enhancement in a 41-year-old woman with progressive dementia. Brain biopsy disclosed axonal spheroids and gliosis in the white matter without macrophage or inflammatory infiltration or vessel abnormalities consistent with neuroaxonal leukodystrophy. This disease can be suspected on CT and MR imaging findings but requires neuropathologic examination to be diagnosed.
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axonal spheroid
brain biopsy
CAT scan,abnormal
corpus callosum
corpus callosum,lesion of
dementia
dementia,frontal lobe type
dementia,presenile
frontal lobe,anatomy and physiology
frontal lobe,lesion of
genu of corpus callosum
leukodystrophy
MRI
MRI,abnormal
neuroaxonal leukodystrophy
white matter disease
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