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In Utero Antiepileptic Drug Exposure: Fetal Death and Malformations
Neurol 67:407-412, Meador,K.J.,et al, 2006
See this aricle in Pubmed
Article Abstract
More adverse outcomes were observed in pregnancies with in utero valproate exposure vs the other antiepileptic drugs (AEDs). These results combined with several recent studies provide strong evidence that valproate poses the highest risk to the fetus. For women who fail other AEDs and require valproate, the dose should be limited if possible.
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adverse drug reaction
anticonvulsants
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anticonvulsants,teratogenicity of
anticonvulsants,untoward effects of
congenital malformation
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intrauterine
mortality
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sodium valproate
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