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Early Coronary Revascularization Diminishes the Risk of Ischemic Stroke with Acute Myocardial Infarction Stroke 37:2546-2551, vanDeGraaff,E.,et al, 2006 See this aricle in Pubmed Article Abstract Risk of in-hospital ischemic stroke with MI is closely tied to the time to revascularization with both thromolytic and percutaneous transluminal coronary angioplasty therapies. Early revascularization is independently predictive of a lower risk of ischemic stroke, but the mechanism of this does not appear to be related to improved cardiac function. The records of 45 997 subjects who received thrombolytic therapy and 47 876 patients who were treated with primary percutaneous transluminal coronary angioplasty for myocardial infarction were analyzed to determine the relationship between time to revascularization and the occurrence of ischemic stroke. A statistically significant linear relationship between time to revascularization therapy and risk of in-hospital ischemic stroke was seen on univariate analysis. A multivariate model incorporating 26 other variables showed thrombolytic therapy within 15 minutes of presentation was associated with a lower risk of ischemic stroke, and angioplasty within 90 minutes was similarly associated with nonsignificant trend toward lower stroke risk.

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(click to filter results - removes previous filter) cerebrovascular accident cerebrovascular accident,prevention of coronary artery bypass myocardial infarction myocardial infarction,acute prevention of neurologic disorders

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