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Twenty-six patients (16 male and 10 female) ranging in age from 5 to 68 years underwent suboccipital transcerebellar stereotaxic biopsy of mass lesions situated in the pons. No complications were encountered in the perioperative period when this technique was used. Histological diagnosis of the lesions revealed: astrocytomas in 14 patients, oligodendroglioma in one, ependymoma in one, cryptococcal abscess in one, demyelinating disease in three, and infarctions in three. Empiric treatment of brain-stem lesions without tissue diagnosis based upon the radiological and clinical findings may result in inappropriate therapy administration. Alternatively, open operative procedures to obtain tissue require a visible surface abnormality to guide biopsy, and carry the risks of a major surgical procedure in already compromised patients. For these reasons the authors consider a suboccipital transcerebellar stereotaxic biopsy to be the diagnostic procedure of choice in the assessment of pontine mass lesions. |
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astrocytoma brain biopsy brain biopsy,stereotaxic brainstem,glioma brainstem,infarction of brainstem,neoplasms of cerebrovascular accident demyelinating disease glioma middle cerebellar peduncle middle cerebellar peduncle,lesion pons,lesion of pontine glioma
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