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Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery (DESTINY)
Stroke 38:2518-2525,2410, Jttler,E.,et al, 2007
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Article Abstract
DESTINY showed that hemicraniectomy reduces mortality in large hemispheric stroke. With 32 patients included, the primary end point failed to demonstrate statistical superiority of hemicraniectomy, and the projected sample size was calculated to 188 patients. Despite this failure to meet the primary end point, the steering committee decided to terminate the trial in light of the results of the joint analysis of the 3 European hemicraniectomy trials.
 
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cerebrovascular accident
cerebrovascular accident,surgical treatment of
controversies in neurology
craniectomy,decompressive
DESTINY
efficacy
middle cerebral artery territory infarction
middle cerebral artery territory infarction,malignant
mortality
review article
treatment of neurologic disorder

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