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Patients with cancer do not manifest symptoms of meningitis as often as patients without cancer and display a very different set of CSF organisms compared to a general population. The CSF inflammatory response is muted in patients with cancer with meningitis. Most patients with cancer with meningitis have had prior neurosurgery. Additionally, the organisms causing meningitis in the cancer population have shifted over time, with a decline in the organisms which typically infect immunocompromised hosts and an increase in Gram-positive infections. |
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carcinoma central nervous system,infection of central nervous system,infection,cancer patient cerebrospinal fluid cerebrospinal fluid,abnormal cryptococcal meningitis fever headache meningismus meningitis meningitis,bacterial meningitis,bacterial-negative CSF culture meningitis,bacteriologic etiology of meningitis,CSF cell count-normal meningitis,CSF findings in meningitis,fungal meningitis,gram negative meningitis,gram positive meningitis,neurologic aspects and complications of meningitis,spinal fluid smear and culture-negative mental status,abnormal mortality neurologic complications of,systemic cancer neurologic symptoms neutropenia pleocytosis of cerebrospinal fluid prognosis review article
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