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Reduction of Disease Activity and Disability With High-Dose Cyclophosphamide in Patients With Aggressive Multiple Sclerosis
Arch Neurol 65:1044-1051, Krishnan,C.,et al., 2008
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Article Abstract
Treatment with HiCy was safe and well tolerated in our patients with MS. Patients experienced a pronounced reduction n disease activity and disability after HiCy treatment. This immunoablative regimen of cyclophosphamide for patients with aggressive MS is worthy of further study and may be an alternative to bone marrow transplantation.
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cyclophosphamide
disability,neurological
efficacy
immunosuppressive agents
MRI,contrast enhanced
multiple sclerosis
multiple sclerosis,acute
multiple sclerosis,aggressive
multiple sclerosis,disability status scale
multiple sclerosis,relapsing
multiple sclerosis,treatment of
safety
treatment of neurologic disorder
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