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Syndrome of Orthostatic Headaches and Diffuse Pachymeningeal Gadolinium Enhancement Mayo Clin Proc 72:400-413, Mokri,B.,et al, 1997 See this aricle in Pubmed Article Abstract The syndrome of low-pressure headaches and pachymeningeal gadolinium enhancement is being recognized with increasing frequency. The source of the CSF leak can be demonstrated in many patients. Meningeal abnormalities are likely attributable to decreased CSF volume and hydrostatic CSF pressure changes. The prognosis is typically good.

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