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Intraventricular Hemorrhage: Severity Factor and Treatment Target in Spontaneous Intracerebral Hemorrhage Stroke 40:1533-1538, Hanley,D.F., 2009 See this aricle in Pubmed Article Abstract Animal models demonstrate clot removal can improve the acute and long-term consequences of intraventricular extension from intracerebral hemorrhage by using minimally invasive techniques coupled to recombinant tissue plasminogen activator-mediated clot lysis. The most recent human clinical trials show that severity of initial injury and the long-term consequences of blood extending into the ventricles are clearly related to the amount of bleeding into the ventricular system. The failure of the last 2 pivotal brain hemorrhage randomized control trials may well relate to the consequences of intraventricular bleeding. Small proof of concept studies, meta-analyses, and preliminary pharmacokinetics studies support the idea of positive shifts in mortality and morbidity, if this 1 critical disease severity factor, IVH, is properly addressed. Understanding clinical methods for the removal of IVH is required if survival and long-term functional outcome of brain hemorrhage is to improve worldwide.

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(click to filter results - removes previous filter) hypertension intraventricular hemorrhage intraventricular hemorrhage,clot evacuation intraventricular hemorrhage,primary intraventricular hemorrhage,treatment prognosis review article treatment of neurologic disorder

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