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Progressive Multifocal Leukoencephalopathy in Individuals with Minimal or Occult Immunosuppression JNNP 81:247-254, Gheuens,S., et al, 2010 See this aricle in Pubmed Article Abstract These results indicate that PML can occur in patients with minimal or occult immunosuppression, and one can revisit the generally accepted notion that profound cellular immunosuppression is a prerequisite for the development of PML.

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