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Apixaban in Patients With Atrial Fibrillation NEJM 364:806-817, Connolly,S.J.,et al, 2011 See this aricle in Pubmed Article Abstract In patients with atrial fibrillation for whom vitamin K antagonist therapy was unsuitable, apixaban reduced the risk of stroke or systemic embolism without significantly increasing the risk of major bleeding or intracranial hemorrhage.

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