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Asymptomatic Spinal Cord Lesions Predict Disease Progression in Radiologically Isolated Syndrome Neurol 76:686-692, 680, Okuda,D.T.,et al, 2011 See this aricle in Pubmed Article Abstract These findings suggest that the presence of asymptomatic spinal cord lesions place subjects with RIS at substantial risk for clinical conversion to either an acute or progressive event, a risk that is independent of brain lesions on MRI.

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