Click Here to return To Results

 

Eccentric Target Sign in Cerebral Toxoplasmosis - Neuropathological Correlate to the Imaging Feature J Magn Reson Imaging 31:1469-1472, Kumar, G.S.,et al, 2010 See this aricle in Pubmed Article Abstract An MR imaging feature on post contrast T1 weighted sequences considered pathognomonic of toxoplasmosis is the ?eccentric target sign?. The pathological correlate of this imaging sign has been speculative. Herein we correlate the underlying histopathology to the MR feature of ?eccentric target sign? in a patient with autopsy proven HIV/AIDS related cerebral toxoplasmosis. The central enhancing core of the target seen on MR imaging was produced by a leash of inflamed vessels extending down the length of sulcus that was surrounded by concentric zones of necrosis and a wall composed of histiocytes and proliferating blood vessels with impaired permeability producing the peripheral enhancing rim.

Related Tags

(click to filter results - removes previous filter) acquired immunodeficiency syndrome CAT scan,abnormal CAT scan,contrast enhanced gadolinium human immunodeficiency virus type 1 MRI MRI,abnormal MRI,contrast enhanced MRI,target sign neuropathology pathognomonic toxoplasmosis,CNS

Click Here to return To Results