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Efficacy and Safety of Everolimus for Subependymal Giant Cell Astrocytomas Associated with Tuberous Sclerosis Complex (EXIST-1): A Multicenter, Randomized, Placebo-Controlled Phase 3 Trial
Lancet 381:125-132, Franz, D.,et al, 2013
See this aricle in Pubmed
Article Abstract
These results support the use of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis. Additionally, everolimus might represent a disease-modifying treatment for other aspects of tuberous sclerosis.
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astrocytoma
efficacy
everolimus
genetic neurologic disorders
neoplasm,primary intracerebral
safety
treatment of neurologic disorder
tuberous sclerosis
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