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Fully-Automated Quantification of Regional Brain Volumes for Improved Detection of Focal Atrophy in Alzheimers Disease
AJNR 30:578-580, Brewer, J.B.,et al, 2009
See this aricle in Pubmed

Article Abstract
Volumetric analysis of structural MR images of the brain may provide quantitative evidence of neurodegeneration and help identify patients at risk for rapid clinical deterioration. This note describes tests of a fully automated MR imaging postprocessing system for volumetric analysis of structures (such as the hippocampus) known to be affected in early Alzheimer disease (AD). The system yielded results that correlated highly with independent computer-aided manual segmentation and were sensitive to the anatomic atrophy characteristic of mild AD.
 
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Alzheimer's disease
biologic markers
brain atrophy
brain volume
dementia
hippocampal atrophy
hippocampus
lobar atrophy
MRI
MRI,abnormal
MRI,morphometyry
MRI,volumetry
temporal lobe
temporal lobe,atrophy
ventricular enlargement

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