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Edoxaban Versus Warfarin in Patients with Atrial Fibrillation NEJM 369:2093-2104, Giugliano, R.P.,et al, 2013 See this aricle in Pubmed Article Abstract Both once-daily regimens of edoxaban were noninferior to warfarin with respect to the prevention of stroke or systemic embolism and were associated with significantly lower rates of bleeding and death from cardiovascular causes.

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