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Neurological Manifestation of Recreational Fatal and Near-Fatal Diethylene Glycol Poisonings
Medicine 93:e62, Imam, Y.Z.B.,et al, 2014
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Article Abstract
Diethylene glycol is a common industrial solvent which is responsible for accidental and epidemic poisoning as early as the 1930s. Due to the unavailability and unaffordability of ethanol, people in Qatar among the low income group are consuming household chemicals, some of which contain diethylene glycol, for recreational purposes. Diethylene glycol is a dangerous substance when ingested and can result in mortality and severe morbidity, particularly from the renal and neurological manifestations. Whereas the mechanism of damage is less well known, the damage is likely dose related. The typical clinical pattern of evolution of the poisoning in the absence of cost-effective ways to detect it in the serum can help clinicians in making the diagnosis. Neurological manifestations may include encephalopathy and multiple cranial and peripheral neuropathies with subsequent brain atrophy. Public awareness of the danger of such recreational use should be raised.
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brain atrophy
cerebral edema
cranial neuropathy
cranial neuropathy,multiple
diethylene glycol
drug abuse
encephalopathy
mortality
MRI,abnormal
neuropathy
poison,neurologic problems with
prognosis
review article
rhabdomyolysis
solvent
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