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This review highlights clinical features of the increasing cases of acute flaccid paralysis associated with anterior myelitis noted in the United States from 2012 to 2015. Acute flaccid myelitis refers to acute flaccid limb weakness with spinal cord gray matter lesions on imaging or evidence of spinal cord motor neuron injury on electrodiagnostic testing. Although some individuals demonstrated improvement in motor weakness and functional deficits, most have residual weakness a year or more after onset. Epidemiological evidence and biological plausibility support an association between enterovirus D68 and the recent increase in acute flaccid myelitis cases in the United States. |
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anterior horn cell disease areflexia arm weakness central nervous system,infection of children cranial neuropathy diarrhea differential diagnosis enterovirus enterovirus infection of CNS epidemiology of neurology fever flaccid paralysis headache infection leg weakness,bilateral meningismus mental status,abnormal motor neuron disease MRI,abnormal MRI,spinal cord myelitis nausea and vomiting neck pain pain pain,back paralysis,acute paralysis,acute areflexic prognosis quadriparesis respiratory tract infection review article spinal cord,lesion of treatment of neurologic disorder viral infection viral infection,CNS
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