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Inflammatory lesions of the pituitary gland are rarely encountered. Recently, the concept of immunoglobulin G4 (IgG4)-related systemic disease was proposed in Japan, and more than 20 cases have been reported as possibly associated with infundibulo-hypophysitis since 2000. We herein review such case reports in the published literature and in the abstracts of scientific meetings. Almost all cases involved middle-aged to elderly men presenting with various degrees of hypopituitarism and diabetes insipidus and demonstrating a thickened pituitary stalk and/or pituitary mass. |
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Addison's disease anorexia diabetes insipidus fever gender headache hypophysitis,IgG4-related hypopituitarism IgG4-related disease lymphadenopathy malaise MRI,abnormal MRI,contrast enhanced neuroendocrinology neurologic complications of,systemic disease pituitary stalk,enlarged pituitary stalk,lesion of pituitary,biopsy pituitary,enlargement pituitary,insufficiency of polyuria steroid therapy,CNS treatment and complications with
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