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Diagnosis of Human Prion Disease Using Real-Time Quaking-Induced Conversion Testing of Olfactory Mucosa and Cerebrospinal Fluid Samples
JAMA Neurol 74:155-162,144, Bongianni, M.,et al, 2017
See this aricle in Pubmed
Article Abstract
A proposed diagnostic algorithm for sporadic CJD combines CSF and OM RT-QuIC testing to provide virtually 100% diagnostic sensitivity and specificity in the clinical phase of the disease.
Related Tags
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cerebrospinal fluid
cerebrospinal fluid,abnormal
Jakob-Creutzfeldt disease
nasal brushings
neurologic disease,diagnoses of
pathognomonic
prion disease
real-time quaking-induced conversion
spongy degeneration of brain
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