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Neurofilament as a Blood Marker for Diagnosis and Monitoring of Primary Progressive Aphasias
Neurol 88:961-969, Steinacker, P.,et al, 2017
See this aricle in Pubmed
Article Abstract
Blood level of NF-L can aid the differential diagnosis of PPA variants, especially in combination with CSF pNF-H. Because serum NF-L correlates with functional decline and atrophy in the disease course, it qualifies as an objective disease status marker. Extended follow-up studies with cases of known neuropathology are imperative.
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aphasia,logopenic,progressive
aphasia,progressive,non-fluent
aphasia,progressive,primary
biologic markers
differential diagnosis
neurofilament light chain protein
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