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In the article we present pathological intracranial substances and lesions, which produce high signal intensity on T1-weighted MR images. Six groups of substances are discussed: 1. Gadolinium � based contrast agents, 2. Hemoglobin degradation products (intra-and extra-cellular methemoglobin), 3. Lipid-containing lesions (lipoma, dermoid cyst, implanted fatty materials, laminar cortical necrosis), 4. Substances with high concentration of proteins (colloid cyst, craniopharyngioma, Rathke�s cleft cyst, ectopic posterior pituitary gland), 5. Melanin (metastatic melanoma), 6. Lesions containing mineral substances such as: calcium (calcifications, Fahr�s disease), copper (Wilson�s disease) and manganese (hepatic encephalopathy, manganese intoxication in intravenous drug abusers). Appropriate interpretation of signal intensity as well as analysis of location of lesions and clinical symptoms enables planning of further diagnostics and, in many cases, establishing the final diagnosis based on MR examination. |
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calcification,intracranial cerebral venous thrombosis craniopharyngioma cyst cyst,dermoid of CNS Fahr disease gadolinium hematoma,epidural-cranial hepatic encephalopathy laminar necrosis,cortical lipoma of CNS manganese intoxication melanoma,malignant methemoglobin MRI,abnormal MRI,contrast enhanced MRI,T1 weighted high signal foci pituitary,adenoma superior sagittal sinus thrombosis
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