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Long-Term Benefit of Enzyme Replacement Therapy in Pompe Disease Neurol 89:2365-2373, Kuperus, E.,et al, 2017 See this aricle in Pubmed Article Abstract Long-term ERT positively affects muscle strength, pulmonary function, and daily life activities in adult patients with Pompe disease, with a peak effect at approximately 2 to 3 years of treatment.

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