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Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing JAMA Neurol 75:947-955,915, Wilson,M.R.,et al, 2018 See this aricle in Pubmed Article Abstract Diverse microbial pathogens wee identified by mNGS in the CSF of patients with diagnostically challenging subacute or chronic meningitis, including a case of subarachnoid neurocysticercosis that defied diagnosis for 1 year, the first reported case of CNS vasculitis caused by Aspergillus oryzae, and the fourth reported case of C dubliniensis meningitis. Priortizing metagenomic data with a scoring algorithm greatly clarified data interpretation and highlighted the problem of attributing biological significance to organisms present in control samples used for metagenomic sequencing studies.

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(click to filter results - removes previous filter) cerebrospinal fluid cerebrospinal fluid,abnormal coinfection infection meningitis meningitis,chronic meningitis,fungal meningitis,helminthic meningitis,viral etiology in neurologic disease,diagnoses of next-generation sequencing

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