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Switching the Manufacturer of Antiepileptic Drugs is Associated with Higher Risk of Seizures: A Nationwide Study of Prescription Data in Germany
Ann Neurol 84:918-925, Lang, J.D.,et al, 2018
See this aricle in Pubmed
Article Abstract
In previously seizure-free patients, switching the manufacturer of antiepileptic medications was associated with a higher risk for seizure recurrence. Our retrospective approach does not allow us to determine whether other changes in medical care at the same time could contribute to the recurrence. However, it would be prudent to avoid switching the manufacturer of anticonvulsants in seizure-free patients.
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