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In a large group of patients with a mitochondrial leukodystrophy, general MR imaging features suggestive of mitochondrial disease were found. Additionally, we identified several MR imaging patterns correlating with specific genotypes. Recognition of these patterns facilitates the diagnosis in future patients. |
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basal ganglia,lesion,bilateral brainstem,lesion of children corpus callosum,lesion of cyst,parenchymal deep gray nuclei gene mutation genetic neurologic disorders Kearns-Sayre syndrome leukodystrophy MELAS syndrome middle cerebellar peduncle,lesion middle cerebellar peduncle,lesion,bilateral mitochondrial disease MNGIE syndrome MRI pattern MRI,abnormal MRI,contrast enhanced MRI,diffusion weighted review article succinate dehydrogenase deficiency symmetric brain lesions thalamus,lesion of-bilateral white matter disease white matter disease,pattern
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