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Clinical and Genetic Spectrum of Mitochondrial Neurogastrointestinal Encephalomyopathy
Brain 134:3326-3332, Garone, C.,et al, 2011
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abdominal distention
areflexia
ataxia
cachexia
cerebellar atrophy,secondary
cerebellar degeneration
consanguinity
creatine phosphokinase(CPK)elevated
deafness
diarrhea
extraocular muscle lesion
familial
gastrointestinal disease,neurologic complications
gastrointestinal motility
gastroparesis
gene mutation
genetic neurologic disorders
heralding manifestation
intestinal pseudoobstruction
leukodystrophy
misdiagnosis
mitochondrial disease
mitochondrial encephalomyopathy
MNGIE syndrome
MRI,abnormal
muscle biopsy
muscle weakness,proximal
neurologic complications of,systemic disease
neurologic disease,diagnoses of
neuropathy
ophthalmoplegia
pain,abdominal
prognosis
progressive neurologic disorder
ptosis
ragged-red fibers
retina,abnormal
retinal lesion
sensorineural hearing loss
systemic illness
weakness
weakness,generalized
weakness,progressive
weaning from respirator,failure to
white matter disease
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